Sterilization of laboratory animal diets using gamma radiation
نویسندگان
چکیده
منابع مشابه
Effect of Gamma Irradiation on Microbial Decontamination, Crude Nutrient Content, and Mineral Nutrient Composition of Laboratory Animal Diets
Laboratory animal models are an important part of test design. Certain conditions such as microbial contamination in diets of these models could affect the results of experiments. One of the most important routes that predispose to contamination is generated through feeding of laboratory animals. This study aimed to show the effect of gamma irradiation in reducing bacteria concentrations,...
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A number of precautions were taken to ensure the accuracy of the analytical procedures and to avoid artifactual formation of N-nitroso compounds. NDPA (5 ng/g), an NDMA analog which is not normally present in the diets, was added to each powdered sample prior to the vacuum distillation step as an internal (recovery) standard. All reported levels of NDMA and NPYR have been adjusted for the recov...
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In the midst of research focusing on the neurodevelopmental effects of mercury vapor in rats, we detected significant levels of mercury (30-60 ng/g) in the blood of nonexposed control subjects. We determined that the dominant form of the mercury was organic and that the standard laboratory chow we used in our vivarium was the source of the contamination. The dietary levels were deemed of potent...
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Sterilization is used in a varity of industry field and a strictly required process for some products used in sterile regions of the body like some medical devices and parenteral drugs. Although there are many kinds of sterilization methods according to physicochemical properties of the substances, the use of radiation in sterilization has many advantages depending on its substantially less tox...
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This study examines the effect of routine gamma radiation based on cobalt 60 on the viability, mosquito larvicidal activity, and density of bacillus spores in the soil. Although 1 g of unirradiated powder of Bacillus thuringiensis israelensis (Bti) contains on average 6.2 x 10(9) spores, no spores survived radiation doses of 20.6 kGy and higher. Radiation at a dose of 20-25 kGy caused a 20-30% ...
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ژورنال
عنوان ژورنال: Laboratory Animals
سال: 1969
ISSN: 0023-6772,1758-1117
DOI: 10.1258/002367769781071790